It can relieve itching immediately, especially when used alongside the “no no itch gel". However, if you’re dealing with severe eczema or in the middle of the healing process, you need to apply the cream very frequently if you are tend to replace or avoid using any Hydrocortisone cream. In addition, you may need to add at least one more layer of cream with a different texture to help lock the moisture, since the skin dries out quickly due to the eczema condition. It would be great if there were a larger volume option available for this cream.